Los Angeles Chargers vs San Francisco 49ers
Friday, August 21, 2026 · 02:00 UTC
Los Angeles Chargers host San Francisco 49ers in the NFL on Friday, August 21, 2026, starting at 02:00 UTC. Here is how the two teams stack up — the head-to-head history, current form and the latest bookmaker odds — ahead of the BetEX AI verdict on this game.
Head-to-head record
These two sides have met 1 time in our head-to-head records, with 0 wins for Los Angeles Chargers against 1 for San Francisco 49ers. Historically, then, San Francisco 49ers have had the better of this fixture. Meetings between the two average 38.0 points per game. Their most recent meeting on record: San Francisco 49ers 22-16 Los Angeles Chargers (2022-11-14).
| Date | Home | Score | Away |
|---|---|---|---|
| 2022-11-14 | San Francisco 49ers | 22-16 | Los Angeles Chargers |
Recent form
Los Angeles Chargers come into this one having won 2 and lost 3 of their last 5 (W-L-L-W-L). Over that run they have scored 142 points and conceded 113. That works out to a 40% form rating over the period.
San Francisco 49ers come into this one having won 4 and lost 1 of their last 5 (L-W-W-W-W). Over that run they have scored 119 points and conceded 141. That works out to a 80% form rating over the period.
🤖 The BetEX AI verdict on Los Angeles Chargers vs San Francisco 49ers
Members see what our model ensemble makes of this game:
- AI pick & win probabilities for every outcome
- Model confidence score
- Key factors behind the call
- Value-bet detection against the market odds
How BetEX AI analyses this fixture
BetEX AI runs every fixture on this page through an ensemble of statistical models — Elo-style team ratings, scoring-rate (lambda) models and head-to-head history — refreshed daily from live competition data. The ensemble produces a win probability for each outcome, a confidence score, and flags games where the model's probability disagrees with the bookmaker line by enough to matter. Those outputs are reserved for members; everything above comes from the same underlying match data.
Predictions and statistics are for informational purposes only and are no guarantee of results. Please bet responsibly — never wager more than you can afford to lose. 18+ only.