NFL

Buffalo Bills vs Los Angeles Chargers

Sunday, September 27, 2026 · 17:00 UTC

Buffalo Bills host Los Angeles Chargers in the NFL on Sunday, September 27, 2026, starting at 17:00 UTC. Here is how the two teams stack up — the head-to-head history, current form and the latest bookmaker odds — ahead of the BetEX AI verdict on this game.

Head-to-head record

These two sides have met 2 times in our head-to-head records, with 2 wins for Buffalo Bills against 0 for Los Angeles Chargers. That gives Buffalo Bills the historical edge in this matchup. Meetings between the two average 45.0 points per game. Their most recent meetings on record: Los Angeles Chargers 22-24 Buffalo Bills (2023-12-24); Buffalo Bills 27-17 Los Angeles Chargers (2020-11-29).

DateHomeScoreAway
2023-12-24Los Angeles Chargers22-24Buffalo Bills
2020-11-29Buffalo Bills27-17Los Angeles Chargers

Recent form

Buffalo Bills come into this one having won 3 and lost 2 of their last 5 (L-W-W-W-L). Over that run they have scored 170 points and conceded 144. That works out to a 60% form rating over the period.

Los Angeles Chargers come into this one having won 2 and lost 3 of their last 5 (W-L-L-W-L). Over that run they have scored 142 points and conceded 113. That works out to a 40% form rating over the period.

🤖 The BetEX AI verdict on Buffalo Bills vs Los Angeles Chargers

Members see what our model ensemble makes of this game:

  • AI pick & win probabilities for every outcome
  • Model confidence score
  • Key factors behind the call
  • Value-bet detection against the market odds
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How BetEX AI analyses this fixture

BetEX AI runs every fixture on this page through an ensemble of statistical models — Elo-style team ratings, scoring-rate (lambda) models and head-to-head history — refreshed daily from live competition data. The ensemble produces a win probability for each outcome, a confidence score, and flags games where the model's probability disagrees with the bookmaker line by enough to matter. Those outputs are reserved for members; everything above comes from the same underlying match data.

Predictions and statistics are for informational purposes only and are no guarantee of results. Please bet responsibly — never wager more than you can afford to lose. 18+ only.