NFL

Buffalo Bills vs Detroit Lions

Friday, September 18, 2026 · 00:15 UTC

Buffalo Bills host Detroit Lions in the NFL on Friday, September 18, 2026, starting at 00:15 UTC. Here is how the two teams stack up — the head-to-head history, current form and the latest bookmaker odds — ahead of the BetEX AI verdict on this game.

Head-to-head record

These two sides have met 2 times in our head-to-head records, with 2 wins for Buffalo Bills against 0 for Detroit Lions. That gives Buffalo Bills the historical edge in this matchup. Meetings between the two average 71.5 points per game. Their most recent meetings on record: Detroit Lions 42-48 Buffalo Bills (2024-12-15); Detroit Lions 25-28 Buffalo Bills (2022-11-24).

DateHomeScoreAway
2024-12-15Detroit Lions42-48Buffalo Bills
2022-11-24Detroit Lions25-28Buffalo Bills

Recent form

Buffalo Bills come into this one having won 3 and lost 2 of their last 5 (L-W-W-W-L). Over that run they have scored 170 points and conceded 144. That works out to a 60% form rating over the period.

Detroit Lions come into this one having won 4 and lost 1 of their last 5 (W-W-L-W-W). Over that run they have scored 181 points and conceded 139. That works out to a 80% form rating over the period.

🤖 The BetEX AI verdict on Buffalo Bills vs Detroit Lions

Members see what our model ensemble makes of this game:

  • AI pick & win probabilities for every outcome
  • Model confidence score
  • Key factors behind the call
  • Value-bet detection against the market odds
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How BetEX AI analyses this fixture

BetEX AI runs every fixture on this page through an ensemble of statistical models — Elo-style team ratings, scoring-rate (lambda) models and head-to-head history — refreshed daily from live competition data. The ensemble produces a win probability for each outcome, a confidence score, and flags games where the model's probability disagrees with the bookmaker line by enough to matter. Those outputs are reserved for members; everything above comes from the same underlying match data.

Predictions and statistics are for informational purposes only and are no guarantee of results. Please bet responsibly — never wager more than you can afford to lose. 18+ only.